Research

Wang, Y., Sonani, R. R., Marshall, L., Bianco, S., Marshall, K., Pincham, A., Yang, H., Serpell, L. C., Seddon, A. M., Egelman, E. H., Thomson, A. R., Adams, D. J. (2025) Self-assembly of off-target peptide sequences: implications for the design of soft materials. Small, (doi: 10.1002/smll.202507714)

Marshall, O., Sutherland, A. (2025) Expanding the fluorescent toolkit: molecular design, synthesis and biological application of unnatural amino acids. Chemical Science,

Burianova, V. K., Zeng, L., Thom, A. W., Radcliffe-Kennedy, N. C., Magennis, S., Sutherland, A. (2025) Environment-sensitive fluorescent tryptophan analogues via indole C-2 alkenylation reactions. Chemical Communications, 61, pp. 11621-11624. (doi: 10.1039/D5CC02114F)

Marshall, O., Sutherland, A. (2025) One-pot synthesis of alkynyl-conjugated phenylalanine analogues for peptide-based fluorescent imaging. Organic Letters, 27, pp. 8023-8027. (doi: 10.1021/acs.orglett.5c02361)

Brettell, S. B., Cann, G., Begen, A., Sharma, S., Mahindra, A., Carruthers, L. V., Milligan, G., Clarke, D. J., Tobin, A. B., Jamieson, A. G. (2025) Lysine targeting covalent inhibitors of malarial kinase PfCLK3. RSC Medicinal Chemistry, (doi: 10.1039/d5md00335k)

Waddell, L. J.N., Okunade, O. A.M., Dodds, A. C., Lok, M. C.H., Khanizeman, R. N., Sutherland, A. (2025) Iron-catalyzed thioarylation of arenes using saccharin-derived reagents. Journal of Organic Chemistry, 90, pp. 5564-5573. (doi: 10.1021/acs.joc.5c00250)

Burianova, V. K., Mcerlain, H., Sutherland, A. (2025) Transition-metal-mediated radiohalogenation using aryl boron reagents. Synthesis, 57, pp. 1402-1414. (doi: 10.1055/s-0043-1775408)

Zeng, L., Marshall, O., McGrory, R., Clarke, R., Brown, R. J., Kadodwala, M., Thomson, A. R., Sutherland, A. (2025) Synthesis of fluorescent dibenzofuran α-amino acids: conformationally rigid analogues of tyrosine. Organic Letters, 27, pp. 2475-2479. (doi: 10.1021/acs.orglett.5c00433)

Morgan, D. C., McDougall, L., Knuhtsen, A., Buetow, L., Steven, C. F., Shepperson, O., Huang, D. T., Hulme, A. N., Jamieson, A. G. (2025) Raman active diyne-Girder conformationally constrained p53 stapled peptides bind to MDM2 for visualisation without fluorophores. RSC Chemical Biology, 6, pp. 394-403. (doi: 10.1039/D4CB00288A)

Eaglesfield, R., Fernandez-Vizarra, E., Lacko, E., Caldwell, S. T., Sloan, N. L., Siciarz, D., Hartley, R. C., Tokatlidis, K. (2025) Sub-organellar mitochondrial hydrogen peroxide observed using a SNAP tag targeted coumarin-based fluorescent reporter. Redox Biology, 80, (doi: 10.1016/j.redox.2025.103502)

Marshall, O., McGrory, R., Songsri, S., Thomson, A. R., Sutherland, A. (2025) Expedient discovery of fluorogenic amino acid-based probes via one-pot palladium-catalysed arylation of tyrosine. Chemical Science, 16, pp. 3490-3497. (doi: 10.1039/D5SC00020C)

Morgan, T. E. F., Grant, E. K., Shaw, R. C., Waddell, L. J. N., Henry, M. C., McErlain, H., Alcaide-Corral, C. J., Pimlott, S. L., Tavares, A. A. S., Sutherland, A. (2025) Synthesis and evaluation of 6-arylaminobenzamides as positron emission tomography imaging ligands for the sphingosine-1-phosphate-5 receptor. RSC Medicinal Chemistry, (doi: 10.1039/D4MD00929K)

Luk, C. et al. (2025) Paracrine role of endothelial IGF-1 receptor in depot-specific adipose tissue adaptation in male mice. Nature Communications, 16, (doi: 10.1038/s41467-024-54669-1)

Brettell, S. B., Janha, O., Begen, A., Cann, G., Sharma, S., Olaniyan, N., Yelland, T., Hole, A. J., Alam, B., Mayville, E., Gillespie, R., Capper, M., Fidock, D. A., Milligan, G., Clarke, D. J., Tobin, A. B., Jamieson, A. G. (2024) Targeting PfCLK3 with covalent inhibitors: a novel strategy for malaria treatment. Journal of Medicinal Chemistry, 67, pp. 18895-18910. (doi: 10.1021/acs.jmedchem.4c01300)

Vosbein, P., Vergara, P. P., Huang, D. T., Thomson, A. R. (2024) An engineered ubiquitin binding coiled coil peptide. Chemical Science, 15, pp. 15776-15782. (doi: 10.1039/d4sc04204b)

Chaubey, S. K., Kumar, R., Lalaguna, P. L., Kartau, M., Bianco, S., Tabouillot, V., Thomson, A. R., Sutherland, A., Lyutakov, O., Gadegaard, N., Karimullah, A. S., Kadodwala, M. (2024) Ultrasensitive Raman detection of biomolecular conformation at the attomole scale using chiral nanophotonics. Small, 20, (doi: 10.1002/smll.202404536)

Vosbein, P., Paredes Vergara, P., Huang, D. T., Thomson, D. (2024) AlphaFold ensemble competition screens enable peptide binder design with single-residue sensitivity. ACS Chemical Biology, 19, pp. 2198-2205. (doi: 10.1021/acschembio.4c00418)

Faragher, R. G. A., Hartley, R. C. (2024) Drug discovery for ageing: SIMPs, NEDs and screening challenges. Nature Reviews Drug Discovery, 23, pp. 725-726. (doi: 10.1038/d41573-024-00087-3)

Masclef, J.-B., Acs, E. M. N., Koehnke, J., Prunet, J., Schmidt, B. V.K.J. (2024) PEGose block poly(lactic acid) nanoparticles for cargo delivery. Macromolecules, 57, pp. 6013-6023. (doi: 10.1021/acs.macromol.4c00528)

Songsri, S., McErlain, H., Sutherland, A. (2024) Stereoselective synthesis of meso- and L,L-diaminopimelic acids from enone-derived α-amino acids. Journal of Organic Chemistry, 89, pp. 10363-10370. (doi: 10.1021/acs.joc.4c00916)

Riley, L. M., Marshall, O., Harkiss, A. H., Senn, H. M., Sutherland, A. (2024) Synthesis of β-pyridyl α-amino acids: conformationally sensitive charge transfer-based fluorophores. Organic Letters, 26, pp. 5391-5395. (doi: 10.1021/acs.orglett.4c01951)

Masclef, J.-B., Prunet, J., Schmidt, B. V.K.J. (2024) Synthesis of PEG-polycycloether block copolymers: poloxamer mimics containing a rigid helical block. Advanced Science, 11, (doi: 10.1002/advs.202310277)

Clarke, R., Zeng, L., Atkinson, B. C., Kadodwala, M., Thomson, A. R., Sutherland, A. (2024) Fluorescent carbazole-derived α-amino acids; structural mimics of tryptophan. Chemical Science, 15, pp. 5944-5949. (doi: 10.1039/D4SC01173B)

Cardwell, P. A., Del Moro, C., Murphy, M. P., Lapthorn, A. J., Hartley, R. C. (2024) Human mitochondrial glutathione transferases: Kinetic parameters and accommodation of a mitochondria-targeting group in substrates. Bioorganic and Medicinal Chemistry, 104, (doi: 10.1016/j.bmc.2024.117712)

Bai, M., Gallen, E., Memarzadeh, S., Howie, J., GAO, X., Kuo, C.-W. S., Brown, E., Swingler, S., Wilson, S. J., Shattock, M. J., France, D. J., Fuller, W. (2024) Targeted degradation of zDHHC-PATs decreases substrate S -palmitoylation. PLoS ONE, 19, (doi: 10.1371/journal.pone.0299665)

Knyzeliene, A., MacAskill, M. G., Alcaide-Corral, C. J., Morgan, T. E., Henry, M. C., Lucatelli, C., Pimlott, S. L., Sutherland, A., Tavares, A. A.S. (2024) [18F]LW223 has low non-displaceable binding in murine brain, enabling high sensitivity TSPO PET imaging. Journal of Cerebral Blood Flow and Metabolism, 44, pp. 397-406. (doi: 10.1177/0271678x231205661)

Dell, M., Tran, M. A., Capper, M. J., Sundaram, S., Fiedler, J., Koehnke, J., Hellmich, U. A., Hertweck, C. (2024) Trapping of a polyketide synthase module after C−C bond formation reveals transient acyl carrier domain interactions. Angewandte Chemie (International Edition), 63, (doi: 10.1002/anie.202315850)

McErlain, H., Andrews, M. J., Watson, A. J.B., Pimlott, S. L., Sutherland, A. (2024) Ligand-enabled copper-mediated radioiodination of arenes. Organic Letters, 26, pp. 1528-1532. (doi: 10.1021/acs.orglett.4c00356)

Chintalapudi, V., Wilson, C., Clark, J. S. (2024) Synthesis of the I-K fused polyether array of CTX3C and related ciguatoxins by use of a gold-catalyzed cyclization reaction. Organic Letters, 26, pp. 769-976. (doi: 10.1021/acs.orglett.3c03782)

Hill, R. A., Sutherland, A. (2024) Hot off the press. Natural Product Reports, 41, pp. 157-161. (doi: 10.1039/d4np90005g)

Waddell, L. J.N., Wilson, C., Sutherland, A. (2024) Trifluoromethylthiolation of Arenes using Lewis acid and Lewis base dual catalysis. Journal of Organic Chemistry, 89, pp. 1275-1284. (doi: 10.1021/acs.joc.3c02571)

Triantafyllakis, M., Alexander, S., Woolford, S., Wilson, C., Clark, J. S. (2023) Synthesis of the A−F fragment of the Pacific ciguatoxin CTX3C by iterative ring-closing metathesis and Tsuji–Trost allylation. Chemistry: A European Journal, 27, (doi: 10.1002/chem.202303121)

Dodds, A. C., Sansom, H. G., Magennis, S. W., Sutherland, A. (2023) Synthesis of Thiazoloindole α‑Amino Acids: Chromophores Amenable to One- and Two-Photon Induced Fluorescence. Organic Letters, 25, pp. 8942-8946. (doi: 10.1021/acs.orglett.3c03851)

Mcguire, K., He, S., Gracie, J., Bryson, C., Zheng, D., Clark, A. W., Koehnke, J., France, D. J., Nau, W. M., Lee, T.-C., Peveler, W. J. (2023) Supramolecular click chemistry for surface modification of quantum dots mediated by Cucurbit[7]uril. ACS Nano, 17, pp. 21585-21594. (doi: 10.1021/acsnano.3c06601)

Sikandar, A., Popoff, A., Jumde, R. P., Mándi, A., Kaur, A., Elgaher, W. A. M., Rosenberger, L., Hüttel, S., Jansen, R., Hunter, M., Köhnke, J., Hirsch, A. K. H., Kurtán, T., Müller, R. (2023) Revision of the absolute configurations of chelocardin and amidochelocardin. Angewandte Chemie International Edition, 62, (doi: 10.1002/anie.202306437)

Dodds, A. C., Waddell, L. J.N., Sutherland, A. (2023) Regioselective functionalization of arenes using iron triflimide catalysis. Synlett, 34, pp. 1852-1865. (doi: 10.1055/s-0042-1751445)

McGrory, R., Clarke, R., Marshall, O., Sutherland, A. (2023) Fluorescent α-amino acids via Heck–Matsuda reactions of phenylalanine-derived arenediazonium salts. Organic and Biomolecular Chemistry, 21, pp. 6932-6939. (doi: 10.1039/d3ob01096a)

Kolling, D., Haupenthal, J., Hirsch, A., Koehnke, J. (2023) Facile production of the Pseudomonas aeruginosa virulence factor LasB in Escherichia coli for structure‐based drug design. ChemBioChem, 24, (doi: 10.1002/cbic.202300185)

Songsri, S., Harkiss, A. H., Sutherland, A. (2023) Synthesis and photophysical properties of charge-transfer based pyrimidine-derived ∝-amino acids. Journal of Organic Chemistry, 88, pp. 13214-13224. (doi: 10.1021/acs.joc.3c01437)

McGrory, R., Morgan, D. C., Jamieson, A. G., Sutherland, A. (2023) Rotamer-controlled dual emissive α-amino acids. Organic Letters, 25, pp. 5844-5849. (doi: 10.1021/acs.orglett.3c02112)

Audic, A., Prunet, J. (2023) Synthesis of the CDF ring system of hexacyclinic acid. Synthesis, 55, pp. 2333-2342. (doi: 10.1055/a-2022-1809)

Morgan, D. C., McDougall, L., Knuhtsen, A., Jamieson, A. G. (2023) Development of bifunctional, Raman active diyne‐girder stapled α‐helical peptides. Chemistry: A European Journal, 29, (doi: 10.1002/chem.202300855)

Waddell, L. J.N., Senkans, M. R., Sutherland, A. (2023) Regioselective C–H thiocyanation of arenes by iron(III) chloride catalysis. Journal of Organic Chemistry, 88, pp. 7208-7218. (doi: 10.1021/acs.joc.3c00454)

Uno, S., Harkiss, A. H., Chowdhury, R., Caldwell, S. T., Prime, T. A., James, A. M., Gallagher, B., Prudent, J., Hartley, R. C., Murphy, M. P. (2023) Incorporating a polyethyleneglycol linker to enhance the hydrophilicity of mitochondria‐targeted triphenylphosphonium constructs. ChemBioChem, 24, (doi: 10.1002/cbic.202200774)

Adam, S., Zheng, D., Klein, A., Volz, C., Mullen, W., Shirran, S. L., Smith, B. O., Kalinina, O. V., Müller, R., Koehnke, J. (2023) Unusual peptide-binding proteins guide pyrroloindoline alkaloid formation in crocagin biosynthesis. Nature Chemistry, 15, pp. 560-568. (doi: 10.1038/s41557-023-01153-w)

Riley, L., Mclay, T. N., Sutherland, A. (2023) Synthesis and fluorescent properties of alkynyl- and alkenyl-fused benzotriazole-derived α-amino acids. Journal of Organic Chemistry, 88, pp. 2453-2463. (doi: 10.1021/acs.joc.2c02886)

Hill, R. A., Sutherland, A. (2023) Hot off the press. Natural Product Reports, 40, pp. 223-227. (doi: 10.1039/D3NP90007J)

Koehnke, J. (2023) Caught in the act. Nature Chemical Biology, 19, pp. 7-8. (doi: 10.1038/s41589-022-01180-7)

Tabouillot, V., Kumar, R., Lalaguna, P. L., Hajji, M., Clarke, R., Karimullah, A. S., Thomson, A. R., Sutherland, A., Gadegaard, N., Hashiyada, S., Kadodwala, M. (2022) Near-field probing of optical superchirality with plasmonic circularly polarized luminescence for enhanced bio-detection. ACS Photonics, 9, pp. 3617-3624. (doi: 10.1021/acsphotonics.2c01073)

McErlain, H., McLean, E. B., Morgan, T. E. F., Burianova, V. K., Tavares, A. A. S., Sutherland, A. (2022) Organocatalytic asymmetric synthesis of SynVesT-1, A synaptic density positron emission tomography imaging agent. Journal of Organic Chemistry, 87, pp. 14443-14451. (doi: 10.1021/acs.joc.2c01895)

She, S., Bell, N. L., Zheng, D., Mathieson, J. S., Castro, M. D., Long, D.-L., Koehnke, J., Cronin, L. (2022) Robotic synthesis of peptides containing metal-oxide-based amino acids. Chem, 8, pp. 2734-2748. (doi: 10.1016/j.chempr.2022.07.007)

Waddell, L., Henry, M., Mostafa, M., Sutherland, A. (2022) One-pot synthesis of diaryl sulfonamides using an iron and copper catalyzed aryl C–H amidation process. Synthesis, 54, pp. 4551-4560. (doi: 10.1055/a-1884-6988)

Archibald, L. J., Brown, E. A., Millard, C. J., Watson, P. J., Robertson, N. S., Wang, S., Schwabe, J. W. R., Jamieson, A. G. (2022) Hydroxamic acid-modified peptide library provides insights into the molecular basis for the substrate selectivity of HDAC corepressor complexes. ACS Chemical Biology, 17, pp. 2572-2582. (doi: 10.1021/acschembio.2c00510)

Miljkovic, J. L., Burger, N., Gawel, J. M., Mulvey, J. F., Norman, A. A. I., Nishimura, T., Tsujihata, Y., Logan, A., Sauchanka, O., Caldwell, S. T., Morris, J. L., Prime, T. A., Warrington, S., Prudent, J., Bates, G. R., Aksentijeviü, D., Prag, H. A., James, A. M., Krieg, T., Hartley, R. C., Murphy, M. P. (2022) Rapid and selective generation of H2S within mitochondria protects against cardiac ischemia-reperfusion injury. Redox Biology, 55, (doi: 10.1016/j.redox.2022.102429)

Atkinson, B. C., Thomson, A. R. (2022) Structured cyclic peptide mimics by chemical ligation. Peptide Science, 114, (doi: 10.1002/pep2.24266)

Mahindra, A., Jenkins, L., Marsango, S., Huggett, M., Huggett, M., Robinson, L., Gillespie, J., Rajamanickam, M., Morrison, A., McElroy, S., Tikhonova, I. G., Milligan, G., Jamieson, A. G. (2022) Investigating the structure–activity relationship of 1,2,4-triazine G-protein-coupled receptor 84 (GPR84) antagonists. Journal of Medicinal Chemistry, 65, pp. 11270-11290. (doi: 10.1021/acs.jmedchem.2c00804)

Cariello, M., Pant, N., Harkiss, A. H., Tracey, F. M., Cameron, J., Skabara, P. J., Holliman, P. J., Docampo, P., Cooke, G. (2022) Synthesis of SOT-OH and its application as a building block for the synthesis of new dimeric and trimeric Spiro-OMeTAD materials. Molecular Systems Design and Engineering, 7, pp. 899-905. (doi: 10.1039/D2ME00038E)

Dodds, A. C., Puddu, S., Sutherland, A. (2022) Thioarylation of anilines using dual catalysis: two-step synthesis of phenothiazines. Organic and Biomolecular Chemistry, 20, pp. 5602-5614. (doi: 10.1039/D2OB01082H)

James, A. M., Norman, A. A. I., Houghton, J. W., Prag, H. A., Logan, A., Antrobus, R., Hartley, R. C., Murphy, M. P. (2022) Native chemical ligation approach to sensitively probe tissue acyl-CoA pools. Cell Chemical Biology, 29, pp. 1232-1244.e5. (doi: 10.1016/j.chembiol.2022.04.005)

Romiti, F., Decultot, L., Clark, J. S. (2022) Convergent synthesis of the C1-C29 framework of amphidinolide F. Journal of Organic Chemistry, 87, pp. 8126-8141. (doi: 10.1021/acs.joc.2c00850)

Burger, N., James, A. M., Mulvey, J. F., Hoogewijs, K., Ding, S., Fearnley, I. M., Loureiro-López, M., Norman, A. A.I., Arndt, S., Mottahedin, A., Sauchanka, O., Hartley, R. C., Krieg, T., Murphy, M. P. (2022) ND3 Cys39 in complex I is exposed during mitochondrial respiration. Cell Chemical Biology, 29, pp. 636-649.e14. (doi: 10.1016/j.chembiol.2021.10.010)

Camargo, L. L., Montezano, A. C., Hussain, M., Wang, Y., Zou, Z., Rios, F. J., Neves, K. B., Alves-Lopes, R., Awan, F. R., Guzik, T. J., Jensen, T., Hartley, R. C., Touyz, R. M. (2022) Central role of c-Src in NOX5- mediated redox signaling in vascular smooth muscle cells in human hypertension. Cardiovascular Research, 118, pp. 1359-1373. (doi: 10.1093/cvr/cvab171)

Sikandar, A., Lopatniuk, M., Luzhetskyy, A., Müller, R., Koehnke, J. (2022) Total in vitro biosynthesis of the thioamitide thioholgamide and investigation of the pathway. Journal of the American Chemical Society, 144, pp. 5136-5144. (doi: 10.1021/jacs.2c00402)

Dodds, A. C., Sutherland, A. (2022) Synthesis of phenoxathiins using an iron-catalysed C–H thioarylation. Organic and Biomolecular Chemistry, 20, pp. 1738-1748. (doi: 10.1039/D2OB00022A)

Ryan, D. G., Knatko, E. V., Casey, A. M., Hukelmann, J. L., Dayalan Naidu, S., Brenes, A. J., Ekkunagul, T., Baker, C., Higgins, M., Tronci, L., Nikitopolou, E., Honda, T., Hartley, R. C., O’Neill, L. A.J., Frezza, C., Lamond, A. I., Abramov, A. Y., Arthur, J. S. C., Cantrell, D. A., Murphy, M. P., Dinkova-Kostova, A. T. (2022) Nrf2 activation reprograms macrophage intermediary metabolism and suppresses the type I interferon response. iScience, 25, (doi: 10.1016/j.isci.2022.103827)

Hill, R. A., Sutherland, A. (2022) Hot off the press. Natural Product Reports, 39, pp. 217-221. (doi: 10.1039/D2NP90004A)

Yelland, T., Garcia, E., Parry, C., Kowalczyk, D., Wojnowska, M., Gohlke, A., Zalar, M., Cameron, K., Goodwin, G., Yu, Q., Zhu, P.-C., Elmaghloob, Y., Pugliese, A., Archibald, L., Jamieson, A., Chen, Y. X., McArthur, D., Bower, J., Ismail, S. (2022) Stabilization of the RAS:PDE6D complex is a novel strategy to inhibit RAS signaling. Journal of Medicinal Chemistry, 65, pp. 1898-1914. (doi: 10.1021/acs.jmedchem.1c01265)

Prag, H. A., Pala, L., Kula-Alwar, D., Mulvey, J. F., Luping, D., Beach, T. E., Booty, L. M., Hall, A. R., Logan, A., Sauchanka, V., Caldwell, S. T., Robb, E. L., James, A. M., Xu, Z., Saeb-Parsy, K., Hartley, R. C., Murphy, M. P., Krieg, T. (2022) Ester prodrugs of malonate with enhanced intracellular delivery protect against cardiac ischemia-reperfusion injury in vivo. Cardiovascular Drugs and Therapy, 36, pp. 1-13. (doi: 10.1007/s10557-020-07033-6)

Ojeda Porras, A. C., Aouzal, R., Wilson, C., Prunet, J. (2022) Relay ring-closing metathesis strategies towards the synthesis of the ABC tricycle of Taxol. Tetrahedron, 106-07, (doi: 10.1016/j.tet.2022.132630)

Neckebroeck, A., Kelly, S. M., Smith, B. O., Clark, J. S. (2022) Synthesis of the prototypical cyclopropyl dipeptide mimic and evaluation of its turn-inducing capability. Journal of Organic Chemistry, 87, pp. 258-270. (doi: 10.1021/acs.joc.1c02344)

Decultot, L., Clark, J. S. (2022) Synthetic studies on amphidinolide F: exploration of macrocycle construction by intramolecular Stille coupling. Organic Letters, 24, pp. 7600-7604. (doi: 10.1021/acs.orglett.2c03045)

Mcerlain, H., Riley, L. M., Sutherland, A. (2021) Palladium-catalyzed C—P bond-forming reactions of aryl nonaflates accelerated by iodide. Journal of Organic Chemistry, 86, pp. 17036-17049. (doi: 10.1021/acs.joc.1c02172)

MacAskill, M. G., Wimberley, C., Morgan, T. E. F., Alcaide‑Corral, C. J., Newby, D. E., Lucatelli, C., Sutherland, A., Pimlott, S. L., Tavares, A. A. S. (2021) Modelling [18F]LW223 PET data using simplified imaging protocols for quantification of TSPO expression in the rat heart and brain. European Journal of Nuclear Medicine and Molecular Imaging, 49, pp. 137-145. (doi: 10.1007/S00259-021-05482-1)

Mahindra, A., Tejeda, G., Rossi, M., Janha, O., Herbert, I., Morris, C., Morgan, D. C., Beattie, W., Montezano, A. C., Hudson, B., Tobin, A. B., Bhella, D., Touyz, R. M., Jamieson, A. G., Baillie, G. S., Blair, C. M. (2021) Peptides derived from the SARS-CoV-2 receptor binding motif bind to ACE2 but do not block ACE2-mediated host cell entry or pro-inflammatory cytokine induction. PLoS ONE, 16, (doi: 10.1371/journal.pone.0260283)

Carter, R. N. et al. (2021) The hepatic compensatory response to elevated systemic sulfide promotes diabetes. Cell Reports, 37, (doi: 10.1016/j.celrep.2021.109958)

Morgan, T. E.F., Riley, L. M., Tavares, A. A.S., Sutherland, A. (2021) Automated Radiosynthesis of cis- and trans-4-[18F]Fluoro-L-proline using [18F]Fluoride. Journal of Organic Chemistry, 86, pp. 14054-14060. (doi: 10.1021/acs.joc.1c00755)

Brooks, S., Charlton, G., Letort, A., Prunet, J., Bucher, G. (2021) Calculations on the ruthenium-catalyzed diene and dienyne ring-closing metathesis reactions in the synthesis of taxol derivatives. Journal of Organic Chemistry, 86, pp. 13056-13070. (doi: 10.1021/acs.joc.1c01879)

Franz, L., Kazmaier, U., Truman, A. W., Koehnke, J. (2021) Bottromycins - biosynthesis, synthesis and activity. Natural Product Reports, 38, pp. 1659-1683. (doi: 10.1039/D0NP00097C)

Scott, A. J., Niitsu, A., Kratochvil, H. T., Lang, E. J. M., Sengel, J. T., Dawson, W. M., Mahendran, K. R., Mravic, M., Thomson, A. R., Brady, R. L., Liu, L., Mulholland, A. J., Bayley, H., DeGrado, W. F., Wallace, M. I., Woolfson, D. N. (2021) Constructing ion channels from water-soluble α-helical barrels. Nature Chemistry, 13, pp. 643-650. (doi: 10.1038/s41557-021-00688-0)

Cairns, A. G., McQuaker, S. J., Murphy, M. P., Hartley, R. C. (2021) Insights on targeting small molecules to the mitochondrial matrix and the preparation of MitoB and MitoP as exomarkers of mitochondrial hydrogen peroxide. Humana

Morgan, D. C., Morris, C., Mahindra, A., Blair, C. M., Tejeda, G., Herbert, I., Turnbull, M. L., Lieber, G., Willett, B. J., Logan, N., Smith, B., Tobin, A. B., Bhella, D., Baillie, G. S., Jamieson, A. G. (2021) Stapled ACE2 peptidomimetics designed to target the SARS-CoV-2 spike protein do not prevent virus internalisation. Peptide Science, 113, (doi: 10.1002/pep2.24217)

Rhys, G. G., Dawson, W. M., Beesley, J. L., Martin, F. J.O., Brady, R. L., Thomson, A. R., Woolfson, D. N. (2021) How coiled-coil assemblies accommodate multiple aromatic residues. Biomacromolecules, 22, pp. 2010-2019. (doi: 10.1021/acs.biomac.1c00131)

Caldwell, S. T., O'Byrne, S., Wilson, C., Cvetko, F., Murphy, M. P., McCarron, J. G., Hartley, R. C. (2021) Photoactivated release of membrane impermeant sulfonates inside cells. Chemical Communications, 57, pp. 3917-3920. (doi: 10.1039/D0CC07713E)

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